E. coli SbcCD and RecA Control Chromosomal Rearrangement Induced by an Interrupted Palindrome

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E. coli SbcCD and RecA Control Chromosomal Rearrangement Induced by an Interrupted Palindrome

Survival and genome stability are critical characteristics of healthy cells. DNA palindromes pose a threat to genome stability and have been shown to participate in a reaction leading to the formation of inverted chromosome duplications centered around themselves. There is considerable interest in the mechanism of this rearrangement given its likely contribution to genome instability in cancer ...

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ژورنال

عنوان ژورنال: Molecular Cell

سال: 2010

ISSN: 1097-2765

DOI: 10.1016/j.molcel.2010.06.011